RPI researchers find drug combo that may treat COVID

Benita Zahn
Updated: April 28, 2021 06:33 PM
Created: April 28, 2021 06:02 PM

We know Remdesivir may shorten the time it takes to recover from COVID-19. Now that anti-viral has been paired with another one, an older drug that used to treat hepatitis C. Combined, the power is greater than either drug alone.

That synergy was discovered by researchers at RPI.

Combining the drugs, explains Dr. Gaetano Montelione, could shortcut the virus, stopping it before it could overwhelm the body. Montelione says this would have a major impact in saving lives.

The power of Remdesivir to stop the virus from replicating is enhanced by the addition of the Hep C drug even though the exact mechanism isn't fully understood.

So far, the work has only been in the lab, but the effectiveness is impressive.

Because Remdesivir is delivered intravenously, this combo drug would need to be fashioned into a pill to work the way Dr. Montelione envisions. Much work is still ahead.

Montelione hopes this research, done with virologists at Mount Sinai in New York, will capture the attention of a drugmaker.


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